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Thursday, June 3, 2021

Introduction to Breast cancer, what is the breast cancer

 Introduction to Breast cancer, what is the breast cancer

    Breast cancer is one of the most common malignant tumors of women. According to statistics, the incidence is 7-10% of the whole body of various malignant tumors. It is only related to genetics, and 40-60. 

    The incidence of women before and after menopausal is high, and only about 1-2% of the breast patient is male. The malignant tumor typically occurring in a breast epithelial tissue. It is one of the most common malignant tumors that seriously affect women's physical and mental health and even life, and breast cancer is rare. 

    The cause of breast cancer has not been fully understood. The study found that there is a certain regularity of breast cancer, and women with high risk factors with breast cancer are prone to breast cancer.

Common Types: Luminal Type, Luminal B (HER-2 negative), Luminal B (HER2 positive), HER2 positive, three negative

Targeting treatment: First consider surgical treatment and endocrine therapy, the whole body treatment recommendation scheme is as follows:

Luminal AMost patients only need endocrine treatment
Luminal B(HER-2 Negative)All patients need endocrine treatment, most patients need to chemotherapy
Luminal B(HER-2 PositiveHER2 targeted drug + chemotherapy + endocrine treatment
HER-2 Positive(non-Luminal)HER2 targeting drug + chemotherapy
Three negativeChemotherapy, PARP1 inhibitors are in clinical experiments

Pathogenic factors: hormone level, benign breast disease, BRCA1 / BRCA2 gene mutation, etc.


High-risk population: BRCA1 / BrCA2 gene mutant carrier, family genetic history.


Early screening: Early multidamine molybdenum target examination and combined B-ultrasound and clinical medical examination are not recommended for non-high-risk populations under 40 years old.


Early symptoms: breast mass, skin depression, nipple overflow and endochard.


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